SARMS-Selective Androgen Receptor Modulators


In the world of fitness and bodybuilding, the quest for the perfect supplement to enhance muscle growth and performance has led to the rise of Selective Androgen Receptor Modulators, or SARMs.

If you’ve been curious about SARMs and their potential benefits, this comprehensive guide will provide you with all the essential information you need to know. From understanding what SARMs are and how they work, to exploring the different types available, their benefits, potential risks, safe usage, and where to find them, we will cover it all.

Whether you’re a seasoned athlete or just beginning your fitness journey, this article aims to equip you with the knowledge to make informed decisions about incorporating SARMs into your regimen. So, let’s delve into the world of SARMs and demystify the facts and myths surrounding these increasingly popular supplements.

Key Takeaways:

  • SARMs are a type of performance-enhancing drug that can increase muscle mass, improve bone health, and enhance fat loss with fewer side effects compared to steroids.
  • Some popular types of SARMs include Ostarine, Ligandrol, and RAD140, each with its own specific benefits and potential risks.
  • When using SARMs, it is important to follow recommended dosages and use post-cycle therapy for safety. Alternatively, there are safe and legal alternatives available for purchase.

What Are SARMs?

What Are SARMs - sarms

Selective Androgen Receptor Modulators (SARMs) are a class of anabolic therapies that selectively target androgen receptors in the body.

These compounds are designed to mimic the effects of testosterone, promoting muscle growth, bone density, and strength without the negative side effects often associated with anabolic steroids. SARMs exert their function by binding to androgen receptors in a tissue-selective manner, which allows them to exhibit their anabolic effects in specific tissues such as muscles and bones, while minimizing unwanted androgenic effects in other tissues.

Due to their selective targeting, SARMs have gained attention as performance-enhancing products, particularly in the fitness and bodybuilding communities. Athletes and fitness enthusiasts often use them to improve muscle mass, strength, and performance without the adverse effects linked to traditional anabolic steroids.

What Does SARMs Stand For?

SARMs is an acronym for Selective Androgen Receptor Modulators, which are recognized as tissue-selective anabolic therapies.

This means that they have the potential to offer the benefits of traditional anabolic steroid medications, such as increased muscle mass and strength, without the same level of androgenic side effects. The tissue selectivity of SARMs allows them to specifically target androgen receptors in muscle and bone tissue, making them a promising option for a range of medical conditions.

The clinical application of SARMs extends to potential treatments for muscle wasting, osteoporosis, and hypogonadism, among other conditions. The targeted approach of SARMs distinguishes them from traditional androgen receptor modulators, offering a new dimension to the realm of anabolic therapies.

How Do SARMs Work?

SARMs exert their effects by interacting with androgen receptors in a selective manner, contributing to their potential for enhancing physical performance while minimizing adverse effects on consumer safety.

Through this selective interaction, SARMs can target specific tissues such as muscle and bone, which are the main sites of androgen action. This targeted approach enhances their potential for improving muscle mass, bone density, and physical strength, while minimizing the risk of unwanted side effects commonly associated with traditional anabolic steroids.

What Are The Different Types Of SARMs?

What Are The Different Types Of SARMs - sarms

There are several types of SARMs available, each with unique properties and potential benefits, including Ostarine (MK-2866), Ligandrol (LGD-4033), Andarine (S4), Cardarine (GW-501516), RAD140 (Testolone), YK-11, S-23, and SR9009 (Stenabolic).

Each SARM has specific properties and benefits. For example, Ostarine is known for promoting lean muscle mass and improving bone density. Ligandrol, on the other hand, is valued for its potential to increase muscle mass and strength. Andarine is recognized for its ability to enhance fat loss and improve muscle strength. Cardarine, often mistaken for a SARM, is actually a PPAR-delta receptor agonist, and it is revered for its potential to boost endurance and metabolism.

RAD140, also known as Testolone, is highly regarded for its anabolic effects on muscle tissue, making it a popular choice for bodybuilders and athletes. YK-11 is a myostatin inhibitor, which means it has the potential to promote muscle growth beyond genetic limitations.

S-23 is recognized for its ability to increase muscle mass and bone density and is considered a promising alternative to traditional androgen therapies. SR9009, or Stenabolic, is famous for its potential to enhance endurance and reduce body fat, making it a valuable compound for performance enhancement.

Ostarine (MK-2866)

Ostarine, also known as MK-2866, is a type of SARM developed by Ligand Pharmaceuticals, recognized for its potential in promoting muscle growth and preserving lean tissue.

It was initially created to prevent muscle wasting, and has gained popularity in the fitness and bodybuilding communities for its ability to enhance endurance and stamina. As a product of selective androgen receptor modulators (SARMs), Ostarine is designed to target androgen receptors in skeletal muscle tissue, supporting the growth and recovery of muscle fibers while also aiding in the preservation of lean body mass. With these attributes, this compound offers a promising alternative for individuals aiming to improve their physical performance and overall body composition.

Ligandrol (LGD-4033)

Ligandrol, also known as LGD-4033, is another type of SARM associated with the research conducted by Dalton Miller, showcasing potential benefits in improving muscle mass and bone density.

Ligandrol, developed as a selective androgen receptor modulator, has garnered attention due to its ability to stimulate muscle growth and enhance bone strength. Dalton Miller’s studies have shed light on its promising effects on muscle mass and its potential to address certain muscle-wasting conditions. It works by targeting androgen receptors in the body, enhancing protein synthesis and promoting anabolism, which aids in muscle building and recovery.

In addition, Ligandrol has been linked to promoting bone health by increasing mineral density and reducing the risk of fractures. This has sparked further interest in its potential applications in treating conditions like osteoporosis.

Andarine (S4)

Andarine, also known as S4, has been linked to research conducted at the University of Tennessee, demonstrating potential advantages in enhancing muscle strength and bone health.

The University of Tennessee’s research on Andarine (S4) has revealed its remarkable potential to improve muscle strength and bone health. This selective androgen receptor modulator (SARM) has shown promising results in stimulating muscle growth and enhancing bone density, making it an area of great interest for athletes and individuals focusing on physical performance. The scientific validation of Andarine contributes to its credibility as a supplement for improving overall physical strength and bone structure.

Cardarine (GW-501516)

Cardarine, also known as GW-501516, has garnered attention from organizations like the World Anti-Doping Agency (WADA), showcasing potential benefits in enhancing endurance and fat loss.

Its recognition by the World Anti-Doping Agency (WADA) underscores its impact within the sports community and regulatory scrutiny. The physiological impact of Cardarine is reflected in its ability to enhance endurance, making it a promising option for athletes and fitness enthusiasts seeking to improve their performance.

Its potential for promoting fat loss has garnered interest among individuals looking to achieve their weight management goals. The regulatory scrutiny surrounding Cardarine reflects its potential impact, prompting further exploration of its effects on the human body.

RAD140 (Testolone)

RAD140, also known as Testolone, has raised concerns due to its classification as a potential illegal drug, despite its purported benefits in promoting muscle growth and strength.

Although RAD140 is not yet approved for human consumption, it is widely considered a research chemical and falls within the category of selective androgen receptor modulators (SARMs).

The controversy surrounding its legality stems from its potential for misuse and its classification as a performance-enhancing substance. Proponents of RAD140 point to its ability to target androgen receptors in skeletal muscles, leading to increased protein synthesis and ultimately muscle growth.


YK-11 has gained attention as a compound often associated with dietary supplements, with notable mentions in platforms like GoodRx, highlighting its potential role in increasing muscle mass and strength.

YK-11, a myostatin inhibitor, is recognized for its potential use in dietary supplements aimed at enhancing muscle growth and strength. Its popularity on platforms like GoodRx indicates the growing interest in its physiological benefits. Researchers have been intrigued by its ability to promote muscle development without the androgenic side effects commonly associated with anabolic steroids.

YK-11 has become a subject of interest in the fitness community due to its potential to improve physical performance and support muscle hypertrophy.


S-23 has been subject to prescription errors, raising concerns about its safe usage and the potential risks associated with mismanagement, despite its purported benefits in muscle preservation and fat loss.

Prescription errors involving S-23 have led to heightened scrutiny regarding its proper administration and dosage. The risks associated with inadequately managed prescriptions are exacerbated by the powerful physiological impacts of S-23, making accurate prescription and monitoring crucial.

Despite these challenges, S-23 is touted for its potential to aid in muscle preservation and fat loss, underscoring the importance of proper prescription and oversight to harness its benefits while mitigating the associated risks.

SR9009 (Stenabolic)

SR9009, also known as Stenabolic, has been explored in the context of anabolic therapies, raising considerations regarding its regulatory status and potential oversight by the FDA in relation to its purported benefits in enhancing endurance and metabolism.

Aside from its potential as an anabolic agent, SR9009 has generated interest due to its influence on metabolic processes. Studies have indicated that it might activate certain genes that affect metabolism and lipid production, potentially yielding benefits for individuals looking to optimize their metabolic functions. These findings have prompted scrutiny from the FDA and other regulatory bodies, striving to ensure the safety and efficacy of products entering the market.

What Are The Benefits Of SARMs?

What Are The Benefits Of SARMs - sarms

SARMs offer various benefits, including increased muscle mass, improved bone health, enhanced fat loss, and performance enhancements, positioning them as attractive alternatives to traditional anabolic therapies and performance-enhancing products.

These compounds, known as selective androgen receptor modulators, are designed to target specific androgen receptors in the body. By doing so, they can promote the growth of lean muscle mass, contributing to strength and physical performance improvements.

SARMs have shown potential in supporting bone health, making them valuable not only for athletes but also for individuals looking to maintain overall musculoskeletal wellness.

  • SARMs may aid in reducing body fat, leading to a more defined physique and improved body composition.
  • Unlike traditional anabolic steroids, SARMs have a reduced risk of androgenic side effects, making them a safer option for individuals seeking performance enhancement without compromising their health.

Increased Muscle Mass

One of the key benefits of SARMs is their potential to promote increased muscle mass through targeted interaction with androgens, offering a compelling advantage for individuals seeking muscular development.

Selective androgen receptor modulators, or SARMs, function by selectively binding to androgen receptors in the body, stimulating anabolic activity in muscles without exerting the same level of androgenic effects as traditional anabolic steroids. This targeted mechanism allows for the promotion of lean muscle mass growth while minimizing the risk of unwanted side effects associated with other androgenic compounds.

The precise androgen modulation offered by SARMs plays a pivotal role in promoting muscle hypertrophy and strength gains, contributing to their appeal for athletes, bodybuilders, and individuals engaged in resistance training.

Improved Bone Health

SARMs show promise in improving bone health by leveraging their tissue selectivity, offering potential benefits for individuals seeking enhanced skeletal strength and resilience.

SARMs, or Selective Androgen Receptor Modulators, have garnered attention for their ability to target specific tissues, such as bone, leading to anabolic effects without the unwanted side effects associated with traditional anabolic steroids. This specificity allows them to promote bone mineral density and overall bone health, making them a prospective option for individuals dealing with osteoporosis or other bone-related conditions.

The impact of SARMs on skeletal strength extends beyond bone health alone. By selectively binding to androgen receptors in bone and muscle tissues, SARMs have the potential to enhance muscle mass and strength, further fortifying the skeletal system and supporting overall physical resilience.

Enhanced Fat Loss

SARMs have been associated with enhanced fat loss, presenting an appealing prospect for individuals aiming to manage body composition and overall fitness, positioning them as valuable performance-enhancing products in this regard.

With their selective action on androgen receptors, SARMs offer potential benefits in promoting specific fat loss while preserving lean muscle mass, contributing to an improved body composition.

These compounds have also been recognized for their potential in enhancing endurance and strength, which are crucial aspects of achieving optimal fitness and performance.

By targeting these benefits, individuals can leverage SARMs to support their fitness journeys and achieve their body composition goals effectively.

Increased Strength and Endurance

SARMs have been linked to potential enhancements in strength and endurance, reflecting their appeal as alternatives to conventional approaches, despite concerns about their classification as potential illegal drugs.

These compounds are designed specifically to target androgen receptors in the body, promoting the development of muscle mass and bone density, which is particularly appealing to individuals seeking to enhance their physical performance.

SARMs are believed to have less potential for unwanted side effects commonly associated with anabolic steroids, making them an attractive option for athletes and fitness enthusiasts.

Reduced Side Effects Compared To Steroids

SARMs stand out for their potential to mitigate adverse effects commonly associated with traditional steroids, aligning with the advocacy efforts of organizations like the Council for Responsible Nutrition (CRN) in promoting consumer safety.

SARMS vs Steroids – What is the difference?

Furthermore, SARMs are renowned for their ability to selectively target androgen receptors in muscle and bone tissue, potentially reducing the negative impact on other organs, as often observed with steroids. This comparative advantage has garnered attention from the health and fitness community, with an increasing interest in exploring the potential benefits of SARMs while considering the consumer safety aspects championed by organizations such as the CRN.

What Are The Risks Of Using SARMs?

What Are The Risks Of Using SARMs - sarms

Despite their potential benefits, the use of SARMs presents inherent risks, including legal implications related to their classification as potential illegal drugs and regulatory oversight by the FDA concerning their safety and efficacy.

The legal status of SARMs varies from one country to another, with some regions outright banning their sale and distribution. This creates a complex landscape for users, as they may unknowingly violate laws by possessing or selling these compounds.

The lack of stringent regulation increases the likelihood of encountering counterfeit or adulterated products, posing significant health hazards. Inadequately labeled or contaminated SARMs can lead to serious adverse effects, potentially impacting vital physiological functions such as hormonal balance, lipid metabolism, and cardiovascular health.

It is crucial for individuals to thoroughly understand the legal ramifications and potential health risks associated with SARMs before considering their use, and to seek guidance from healthcare professionals to ensure informed decisions.

How To Use SARMs Safely?

How To Use SARMs Safely - sarms

To ensure safe usage, individuals considering SARMs should adhere to recommended dosages and consider incorporating post cycle therapy (PCT) practices as part of their regimen to mitigate potential adverse effects and support overall well-being.

Avoiding the temptation to exceed the recommended dosages is crucial for maintaining a responsible approach to SARMs usage. Consistent monitoring of the body’s response to the compounds is essential in staying within the prescribed limits.

Integrating post cycle therapy (PCT) into the regimen can aid in restoring hormone levels to their natural state after the completion of a SARMs cycle, thereby minimizing the risk of negative impacts on hormonal balance. It’s important to prioritize overall well-being and follow a comprehensive approach to SARMs usage.

Follow Recommended Dosages

Adherence to recommended dosages is paramount when using SARMs, as deviations can lead to prescription errors and potential health risks, underscoring the importance of precise and responsible usage.

Following the recommended dosages for Selective Androgen Receptor Modulators (SARMs) is a critical aspect of their safe and effective utilization. Compliance with prescribed amounts helps mitigate the risks associated with prescription errors that could arise from inaccurate dosing.

Precise adherence to recommended dosages is essential in preventing the potential health hazards associated with incorrect usage, thereby prioritizing the well-being of individuals engaging in SARMs therapy. Therefore, strict adherence to prescribed dosages serves as a crucial safeguard against the unintended consequences of inappropriate SARMs consumption.

Use PCT (Post Cycle Therapy)

Incorporating post cycle therapy (PCT) as part of a SARMs regimen can contribute to consumer safety by minimizing the potential impacts of hormonal imbalances and supporting a smoother transition post-usage, promoting holistic well-being.

By including post cycle therapy (PCT) in the use of SARMs, individuals can take proactive measures to safeguard their overall health. PCT plays a significant role in restoring hormonal balance, which may be disrupted during the SARMs cycle. This balance is essential for the proper functioning of various bodily systems, thereby preventing any adverse effects on mood, energy levels, and metabolism.

Integrating PCT can help in preserving the hard-earned gains achieved during the SARMs cycle. The therapy aids in retaining muscle mass while promoting the recovery of natural testosterone levels. This not only supports physical well-being but also contributes to mental and emotional stability post-cycle.

Safe and legal SARMs alternatives

Safe and legal SARMs alternatives - sarms

For individuals seeking safe and legal alternatives to SARMs, exploring options endorsed by organizations like the Council for Responsible Nutrition (CRN) can provide reassurance in promoting consumer safety and well-being.

The Council for Responsible Nutrition (CRN) encourages individuals to consider natural supplements, such as protein powders, creatine, and branched-chain amino acids, as effective alternatives to SARMs. These options not only comply with regulatory standards but also offer support for overall health and athletic performance.

Choosing products from reputable manufacturers and understanding the appropriate dosage is essential for informed and responsible supplementation. Addressing dietary needs through wholesome, nutrient-dense foods and consulting a healthcare professional can further contribute to the enhancement of one’s well-being.

Where Can You Buy SARMs?

Where Can You Buy SARMs - sarms

The availability of SARMs can be found through various channels, including platforms like GoodRx, although caution is advised due to concerns regarding the potential prevalence of illegal and unauthorized products in the market.

It is important for consumers to exercise diligence when seeking to purchase SARMs, especially as the heightened demand for these products has led to the increased presence of illegitimate or substandard offerings. Platforms like GoodRx can provide access to a range of SARMs, wherein individuals can compare prices and obtain discounts on legitimate pharmaceutical products. It is crucial to conduct thorough research and verification to ensure the authenticity and safety of the purchased items.

Given the proliferation of unauthorized products, it is advisable to consult healthcare professionals or trusted sources for guidance on legitimate procurement options, emphasizing the significance of consumer protection and safety.

Frequently Asked Questions

What are SARMs?

SARMs, or Selective Androgen Receptor Modulators, are a type of performance-enhancing drug that are designed to target androgen receptors in the body, similar to anabolic steroids.

How do SARMs work?

SARMs work by selectively binding to androgen receptors in specific tissues, such as muscle and bone, without affecting other organs in the body. This allows for targeted muscle and bone growth without the negative side effects of traditional anabolic steroids.

What are the benefits of using SARMs?

Some potential benefits of using SARMs include increased muscle mass, improved athletic performance, and faster recovery from injuries. They can also be used to treat medical conditions such as osteoporosis and muscle wasting diseases.

Are SARMs legal?

SARMs are currently not approved by the FDA for human use and are considered a prohibited substance by the World Anti-Doping Agency. However, they can be legally purchased as research chemicals or for “personal use” purposes.

What are the potential side effects of using SARMs?

While SARMs are marketed as a safer alternative to traditional steroids, they can still have potential side effects such as acne, hair loss, and changes in cholesterol levels. It is important to consult a doctor before using SARMs.

Can SARMs be detected in drug tests?

Yes, SARMs can be detected in drug tests. While they may not show up on standard tests, specialized tests can detect SARMs in the body. Athletes should be aware that using SARMs can result in a positive drug test and potential penalties.